Mug Protein Reagents to Assess DNA Damage and Repair
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- Categories
- Biotechnology
- Summary
- WSU researchers have cloned the gene in E. coli which codes for the Mug Protein, the enzyme that removes ethenocytosine from damaged DNA in the first step in DNA repair. The presence of ethenocytosine can be used as a biomarker for cancer, to evaluate potential carcinogens and to evaluate environmental toxins.
The following biological materials are available for license on a non-exclusive basis: clone encoding the Mug DNA sequence, purified Mug protein, mug- strains, anti-Mug antibodies and antisera. These reagents can be used to assess DNA damage and repair, mutations and environmental toxicology and should be of interest to cancer researchers, toxicologists and molecular biologists.
- File number
- 00-533
- Contact
- Anne DiSante
Director, Technology Transfer Office
Phone: 313-577-5541
Fax : 313-577-2814
anne.disante@wayne.edu