Experimental Bone Metastatic Prostate Tumor Model
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- Categories
- Biotechnology, Pharmaceuticals
- Summary
- A Wayne State University researcher has derived new tumorigenic cell lines from the human prostate carcinoma cell line PC-3. These cell lines, known as PC-3/IF, when implanted in the femurs of nude mice, provide a xenograft tumor model of bone metastatic prostate carcinoma. The PC-3/IF cell lines are highly tumorigenic, with tumor cells replacing the marrow cells in the bone cavity, invading adjacent bone and muscle tissue to ultimately form a palpable tumor at the hip joint.
- File number
- 98-449
- Publications
- Available non-exclusively via biological materials licensing.
- Contact
- Anne DiSante
Director, Technology Transfer Office
Phone: 313-577-5541
Fax : 313-577-2814
anne.disante@wayne.edu