Enzyme-Activated Nitric Oxide Donors
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- Categories
- Biotechnology, Pharmaceuticals
- Summary
- WSU researchers designed and synthesized a series of new pro-drug nitric oxide donor compositions which are activated by particular glycosidases. Using these compounds, site-specific and controlled-release of nitric oxide can be achieved and thus may be useful for regulating many physiological processes. These drugs have shown anti-cancer and anti-viral effects in vitro and may also have applications as vasorelaxants, antithrombotics, or cytostatic or genotoxic compounds.
- File number
- 01-552
- Publications
- U.S. Patent No. 6,867,194 has issued.
- Contact
- Anne DiSante
Director, Technology Transfer Office
Phone: 313-577-5541
Fax : 313-577-2814
anne.disante@wayne.edu