Wayne State University

AIM HIGHER

Technology Commercialization

Method to Identify Anti-Epileptic Targets and Drugs

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Categories
Biotechnology, Pharmaceuticals
Summary
The invention is a two-step process/method to identify new targets and drugs to prevent and treat epilepsy. The first step is to identify targets for the disease through statistical analysis of human brain gene expression from patients with epilepsy vs. controls. The second step is to test drugs known to affect these targets in a novel animal model of epilepsy that focuses on interictal spiking. This approach has already identified a potential drugable pathway that can be modified with existing drugs to treat the disease.
File number
08-888
Data
Data is available upon completion of a confidentiality agreement.
Publications
A patent application will be filed on this invention. We are seeking partners to: 1) develop new drugs to novel epilepsy targets and/or; 2) repurpose existing drugs for an epilepsy indication.
Contact
Randy Ramharack Technology Licensing Manager Phone: 313-577-5541 Fax : 313-577-2814 randy.ramharack@wayne.edu